LABORATOIRE D'ONCOLOGIE VIRALE ET MOLECULAIRE
UFR de Biochimie, Université Paris 7 D. Diderot
2 Place Jussieu
75005 PARIS - FRANCE
 Directeur: Professeur Bernard Perbal
Fax :33 1 44 27 60 43 --- Tel: 33 1 44 27 57 04
Les travaux effectués dans ce laboratoire ont pour objectifs la compréhension des bases moléculaires du développement des tumeurs cancéreuses et la mise au point de protocoles de dépistage précoce, diagnostic, pronostic, et thérapie des tumeurs
Research performed in this laboratory is aimed at understanding the molecular bases of cancer development and establishing new protocols for early diagnosis, pronostic, and therapy of tumors
Thématiques/Themes

Cancérologie /Cancerology
Virologie /Virology
Développement /Development
Travaux en cours/work in progress
 
 

Autres activités/ Other activities
 ccnsociety

Récentes publications , Recent publications

Perbal B. The CCN3 protein and cancer.
Adv Exp Med Biol. 2006;587:23-40. Review.
Fukunaga-Kalabis M, Martinez G, Liu ZJ, Kalabis J, Mrass P, Weninger W, Firth SM, Planque N, Perbal B, Herlyn M.
CCN3 controls 3D spatial localization of melanocytes in the human skin through DDR1.
J Cell Biol. 2006 Nov 20;175(4):563-9. Epub 2006 Nov 13.
Yan X, Baxter RC, Perbal B, Firth SM.
The aminoterminal insulin-like growth factor (IGF) binding domain of IGF binding protein-3 cannot be functionally substituted by the structurally homologous domain of CCN3.
Endocrinology. 2006 Nov;147(11):5268-74. Epub 2006 Aug 24.
Perbal B.
New insight into CCN3 interactions - Nuclear CCN3 : fact or fantasy?
Cell Commun Signal. 2006 Aug 8;4:6.
McCallum L, Price S, Planque N, Perbal B, Pierce A, Whetton AD, Irvine AE.
A novel mechanism for BCR-ABL action: stimulated secretion of CCN3 is involved in growth and differentiation regulation.
Blood. 2006 Sep 1;108(5):1716-23. Epub 2006 May 2.
Planque N, Long Li C, Saule S, Bleau AM, Perbal B.
Nuclear addressing provides a clue for the transforming activity of amino-truncated CCN3 proteins.
J Cell Biochem. 2006 Sep 1;99(1):105-16.
Perbal B.
NOV story: the way to CCN3.
Cell Commun Signal. 2006 Feb 20;4:3.